- 3M—Mescaline, mushrooms (psilocybin) and Molly (crystal Ecstasy)
- A-bomb or atom bomb—Marijuana mixed with heroin
- Amp joint—Marijuana cigarette laced with some form of narcotic
- B-40—Cigar laced with marijuana and dipped in malt liquor
- Back to back—Abuse of heroin followed by crack cocaine or vice versa
- Banana split—Combination of the synthetic 2C-B with other illegal drugs,
especially LSD - Banano—Marijuana or tobacco cigarettes doctored with cocaine
- Bars—Heroin mixed with alprazolam/Xanax
- Basuco—Incompletely refined cocaine paste sprinkled on a marijuana cigarette
- Bazooka—Combination of crack cocaine or unrefined cocaine and marijuana
- Beam me up, Scottie—Cocaine combined with PCP
- Bipping—Snorting heroin and cocaine, either simultaneously or close together
- Black Russian—Hashish and opium
- Buda—High-grade marijuana with crack cocaine added
- Bumping up—Combining Ecstasy with powder cocaine
- C & M—Cocaine and morphine
- Canade—Heroin and marijuana used together
- Candy blunt—Marijuana-filled cigar (blunt) dipped in cough syrup
- Candy flipping—Using LSD and Ecstasy together
- Candy flipping on a string—Combining LSD and Ecstasy or LSD, Ecstasy and cocaine either all at once or in sequence
- Capsizing—PCP and MDMA
- Caviar—Cocaine and marijuana
- Cheese—A mix of black tar heroin and diphenhydramine (most commonly found in Tylenol PM)
- Chasing the dragon—Crack cocaine and heroin
- Chips—Tobacco or marijuana cigarettes treated with PCP
- Chronic—Marijuana mixed with crack
- Clicker—Crack mixed with PCP or a marijuana cigarette treated with dipped in formaldehyde before smoking
- Cocktail—Combination of crack and marijuana
- Cocoa Puffs—Cocaine and Marijuana smoked together
- Crackers—Talwin (narcotic painkiller) and Ritalin
- Crescent roll—Marijuana laced with cocaine
- Crisscrossing—Snorting a line of cocaine along with a line of heroin
- Crunk—Getting high and drunk at the same time.
- Diablito—Crack cocaine and marijuana in a joint
- Dipped joints—Marijuana combined with PCP and formaldehyde
- Dirties/Dirty joints—Marijuana mixed with powder cocaine
- Donk—Marijuana and PCP
- Draf—Ecstasy with cocaine
- Dragon rock—Heroin and crack mixed together
- Dust—Marijuana mixed with various other drugs such as cocaine, heroin or PCP
- Dynamite—Cocaine mixed with heroin
- Eightball—Crack cocaine and heroin
- El diablito—Cocaine, marijuana, heroin and PCP
- El diablo—Cocaine, marijuana and heroin
- Elephant flipping—Use of PCP and Ecstasy with animal anesthetic ketamine
- Ethan—LSD and cocaine
- Fire—Crack and methamphetamine
- Five-way—Snorting heroin, cocaine, methamphetamine, and Rohypnol while also drinking alcohol
- Flamethrowers—Regular cigarettes treated with cocaine and heroin
- Flower flipping—Ecstasy and mushrooms used together
- Frisco special/Frisco speedball—Cocaine, heroin, and LSD
- Fry/Fry sticks—Marijuana cigarettes dipped in embalming fluid or PCP
- Fry daddy—Crack and marijuana mixed and smoked
- Geek-joints—A marijuana cigarette with crack or powdered cocaine added
- Gimmie—Crack and marijuana mixed together
- Goofball—Cocaine and heroin
- Greek—Marijuana and powder cocaine
- H & C—Heroin and cocaine
- H-bomb—Ecstasy and heroin
- Handlebars—Combination of crack cocaine and alprazolam (Xanax)
- Happy stick—Marijuana and PCP in a cigarette
- He-she—Heroin mixed with cocaine
- Herb and al—Marijuana and alcohol
- Hippie flip—Use of mushrooms (psilocybin) and Ecstasy
- Houston cocktail—Hydrocodone, a benzodiazepine like Valium or Xanax, and Soma/carisoprodol
- Hugs and kisses—Combination of methamphetamine and Ecstasy
- Illie/illy—Marijuana dipped in liquid PCP or embalming fluid and then dried
- Jedi flip—Mushrooms, LSD, and Ecstasy
- Jet fuel—PCP use combined with methamphetamine
- Jim Jones—Marijuana treated with cocaine and PCP
- Joy stick—Marijuana treated with PCP
- Juice joint—Marijuana cigarette sprinkled with crack
- Karachi—Heroin, phenobarbital (a sleeping drug), and methaqualone (depressant)
- Killer weed—Marijuana and PCP
- Kitty Bending—Ketamine and benzodiazepines (Xanax, Valium)
- Kitty Boosting—Amphetamine and ketamine
- Kitty Flipping—Ketamine and Ecstasy
- Kitty Tripping—Ketamine and LSD
- Lace—Cocaine and marijuana
- Las Vegas cocktail—Hydrocodone and a benzodiazepine like Valium or Xanax
- LBJ—Heroin plus LSD and PCP
- Liprimo—Marijuana and crack mixed and formed into a cigarette
- Love boat—Marijuana dipped in formaldehyde; a cigar refilled with marijuana
and then dipped in liquid PCP; cigar refilled with marijuana that has heroin added - Love flipping—Mescaline and Ecstasy
- Lucky flip—Ecstasy and synthetic 2C-T-7
- Love trip—Mescaline and Ecstasy
- Lovelies—Marijuana treated with PCP
- Methball—methamphetamine and heroin mixed in one syringe
- Missile basing—Crack and PCP
- Moonrock—Crack and heroin
- Murder one—Heroin and cocaine
- Neon Nod—LSD and heroin
- Nexus flipping—Nexus (the synthetic 2-CB) and MDMA
- Nox—Nitrous oxide and MDMA
- Octane—PCP laced with gasoline
- On the ball—Ecstasy particles added to a bag of heroin
- One and ones—Talwin (narcotic painkiller) and Ritalin
- Oolies—Marijuana cigarettes laced with crack
- Ozone—Cigarette containing marijuana, PCP and crack cigarette
- P-dogs—Cocaine and marijuana
- P-funk—Crack plus PCP
- Pancakes and syrup—Glutethimide (hypnotic drug) and codeine cough syrup
- Parachute—Smoking crack and PCP; smoking crack and heroin
- Parachute down—Using Ecstasy when coming down off heroin
- Party and play—Methamphetamine together with Ecstasy and Viagra
- Party pack—The synthetic 2C-B plus other illicit drugs, particularly Ecstasy
- Pharming—Mixing prescription drugs
- Piggybacking—Simultaneous injecting two drugs; using Ecstasy sequentially to maintain the high
- Pikachu—Pills containing PCP and Ecstasy
- Polo—Heroin and dimenhydrinate (Dramamine)
- Poor man’s heroin—Narcotic painkiller Talwin and Ritalin, injected
- Poro—Heroin plus PCP
- Primos—Marijuana joints treated with crack cocaine
- Quiktrip—Methamphetamine and psilocybin
- Red rock opium/Red rum—Heroin, sleeping pills, strychnine and caffeine
- Ritz and Ts—Ritalin and Talwin, injected
- Robo flipping—Ecstasy and dextromethorphan (cough medication)
- Rompums—Marijuana with Xylazine or other horse tranquilizers
- Sandwich—Two layers of cocaine with a layer of heroin in the middle
- Scramble—Low purity heroin plus crack cocaine
- Screwball—Heroin and methamphetamine
- Serial speedballing—Sequencing cocaine, cough syrup, and heroin over period of days
- Shabu—Powder cocaine and methamphetamine
- Sherman stick—Crack cocaine with marijuana in a blunt (refilled cigar)
- Smoking gun—Heroin and cocaine
- Snowcone—Amphetamine and weed smoked together
- Snow seals—Cocaine and amphetamine
- Space base/Space blunt—Crack dipped in PCP; refilled cigar with PCP and crack
- Space cadet/Space dust—Crack dipped in PCP
- Speedball—Cocaine and heroin; may also refer to methylphenidate (Ritalin) mixed with heroin
- Speedboat—Methamphetamine, PCP, heroin and cocaine or marijuana, PCP and crack smoked together
- Speedkitten—Methamphetamine and ketamine
- Speedies—Ecstasy adulterated with amphetamine
- Spill—Speed and an ecstasy pill in the same line to be snorted
- Splitting—Rolling marijuana and cocaine into a single joint
- Spoke—Speed, crushed Ecstasy pill and coke in the same line to be snorted
- Squirrel—PCP and marijuana that is laced with cocaine and smoked
- Stupor stoning—Drinking alcohol while smoking marijuana
- Sugar flipping—Ecstasy and cocaine
- Super grass—Marijuana treated with PCP
- Super X—Methamphetamine and Ecstasy
- Tar—Smoking crack and heroin
- Tipsy flipping—Alcohol and Ecstasy
- Torpedo—Marijuana and crack
- Troll—LSD and MDMA
- Twisters—Crack and methamphetamine
- Waffle dust—Ecstasy and amphetamine
- Wet/Wet sticks—Marijuana cigarettes soaked in PCP or formaldehyde and dried
- Whack—Heroin and PCP; Crack and PCP
- Wicky—Powder cocaine, PCP and marijuana
- Wild cat—Methcathinone (synthetic similar to methamphetamine) mixed with cocaine
- Wollie/Woo—Adding crack rocks to a marijuana cigarette
- Woola blunt/Woolah- Marijuana and heroin in a refilled cigar
- Woolas—Crack sprinkled on marijuana cigarette
- Woolie—Marijuana and heroin; marijuana and crack cocaine; marijuana and PCP
- Woolies—Marijuana and crack or PCP
- Yerba mala—PCP and marijuana